FORMULATION AND INVITRO EVALUATION OF SOLID DISPERSION TABLETS OF SILYMARIN

Formulation & Evaluation of Oral Disintegrating Tablets of Lamotrigine Solid Dispersions

Lamotrigine is used in the treatment of CNS disorders, particularly epilepsy; pain; oedema; multiple sclerosis and psychiatric indications including bipolar disorder. Lamotrigine belongs to biopharmaceutical classification systems, BCS class II (Low solubility & High permeability). In addition, it requires immediate therapeutic action hence the main objective of this study is to improve the sol...

formulation and evaluation of domperidone fast disintegrating tablets and its taste masking using solid dispersion technology

Formulation and In-vitro Evaluation of Conventional Tablets of Ezetimibe by Using Solid Dispersion

Objective: The objective of the present investigation was to improve dissolution characteristics of EZE, which might offer improved bioavailability. Method: The solid dispersion of Ezetimibe was prepared by Solvent evaporation method by using 1:1, 1:2 and 1:3 ratios of drug and polymers (PVP K-30, Sodium starch glycolate). The tablets were prepared by direct compression method. The compressed t...

Formulation and in Vitro Evaluation of Famotidine Floating Tablets by Lipid Solid Dispersion Spray Drying Technique

The purpose of this investigation was to prepare a gastro retentive drug delivery system of famotidine tablets. Floating tablets of famotidine were prepared employing lipid solid dispersion spray drying technique with gelucire 50/13 and compritol 888 along with HPMC K100M, lactose, sodium bicarbonate and citric acid. The floating tablets were evaluated for uniformity of weight, hardness, friabi...

Formulation and Invitro - Evaluation of Gastro - Retentive Superporous Hydrogel Tablets of Famotidine